For more information contact
Director of Graduate Studies
University Program in Structural Biology and Biophysics
Box 103855 Duke University Medical Center
Durham, NC 27710
General InformationDegree offered:
THE SBB PHD PROGRAM IS NO LONGER ADMITTING STUDENTS. The University Program in Structural Biology and Biophysics at Duke centers on those research endeavors that use physical measurements to study biological macromolecules and their interactions, where the details of molecular structure are critical to understanding the biological problem in question. The focus is on resolving molecular structures at atomic resolution; the breadth extends to detecting molecular events and describing structural relationships in a chemically meaningful way. There is a commonality in the intellectual approaches and experimental techniques. Research problems that fit the paradigm include: 3-D structure determination by crystallography and NMR; many problems approached by various diffraction and microscopy techniques; molecular modeling and design studies which are tied to direct experimental tests; many spectroscopic studies where construction of a molecular model is vital to planning further experiments; and functional studies in biochemistry, genetic mechanisms, drug interactions, membrane systems, etc., for which the details of molecular geometry are central to interpreting the experiments. Students participate in rotations in three laboratories before choosing an advisor.